Antacids: understand the legends and misconceptions.
On the one hand, all the drugs that belong to the group of antacids, can neutralize hydrochloric acid and thus reduce the irritation of the mucous membrane of the stomach and pain syndrome. But in terms of their own composition, pharmacokineticThe following are some of the most important factors in the development of the.
All antacids have the KRALOVNA from Czech to English same effect.
For example, absorbed antacids (sodium bicarbonate, calcium carbonate) are very fast, but short-lived, can cause ricochet syndrome, and with frequent use lead to alkalosis (alkalization). The effect of non-absorbable drugs (magnesium and aluminum hydroxides) does not develop as rapidly, but lasts for 3-4 hours, and antacids of this group have a cytoprotective effect on the gastric mucosal system.
Among the antacids are drugs that can neutralize not only hydrochloric acid, and pepsin, bile acids, and regulate the motility of the intestinal tract, enrich the regeneration of ulcers and erosions. So the similar effect of these different antacids can not be called.
Antacids are the only cure for heartburn.
Heartburn, t.е. a burning sensation behind the sternum, appears in this case, when the acidic contents of the stomach are taken into the food tract and cause a chemical burn of its mucous membrane. To cope with heartburn, you can use antacids, and you can solve this problem with the help of drugs from other pharmaceutical groups.
For example, in cases of frequent recurrences of heartburn against the background of acid-dependent diseases , H2-histamine receptor blockers and proton pump inhibitors are recommended, which can inhibit the formation of hydrochloric acid and thus prevent the occurrence of heartburn.
As a candidate antacids can be used alginates (salts of alginic acid), which in cooperation with acidic gastric juice form a gel. A layer of gel on the surface of the stomach contents prevents reflux and protects the mucosa from heartburn. In some cases (with peptic ulcer disease, acquired gastroduodenitis, and gastritis), the best way to heal heartburn is to use gastroprotectors – bismuth preparations, sucralfate, etc.д.
Instead of antacids, it is better to use ordinary baking soda.
Drinking soda, or sodium bicarbonate, very quickly reduces the acidity of gastric juice, but this effect lasts only a couple of minutes, t.к. in response to a sharp change in the pH of the stomach, a ricochet syndrome develops – a secondary increase in the secretion of hydrochloric acid. As a result, the content of acid in the gastric juice increases, irritation of the mucous membrane and heartburn increases. The accumulation of carbon dioxide in the stomach, which is released with the help of sodium bicarbonate and hydrochloric acid, also contributes to this. The gas stretches the walls of the stomach, provokes acid reflux, and increases pain. If in this situation, however, the person takes the newest dose or even several, it can lead to systemic side effects – nausea, vomiting, migraine, and edema. Soda is especially unsafe for patients with kidney disease and cardiovascular disease.
Antacids help with heaviness, belching, or overfilling of the stomach.
Many patients perceive antacids as drugs that “help the stomach. And try to use them not only to relieve heartburn, and as a means of first aid for symptoms of gastric dyspepsia – a feeling of fullness after eating, heaviness in the stomach, flatulence and belching air. But it is not the extra secretion of hydrochloric acid that underlies the development of these nasty feelings. A prerequisite may be impaired gastrointestinal motility, increased sensitivity of visceral receptors and impaired nervous regulation of the stomach, lack of activity of digestive enzymes and other multifunctional disorders. Taking antacids in this situation will only help to relieve heartburn, but will not affect all other symptoms. And if there is no heartburn, taking antacids is useless. In some cases, it can even be harmful, for example, if dyspepsia is associated with reduced acidity of gastric juice. Therefore, to heal the symptoms of dyspepsia, it is recommended to use prokinetics, enzyme preparations and agents that reduce gas formation in the gastrointestinal tract.
Antacids are useless for gastritis and peptic ulcer disease.
Antacids, although not a basic therapy product, are very extensively used in the treatment of acid-dependent diseases. First, in peptic ulcer disease and hyperacidic gastritis, antacids are one of the more effective symptomatic drugs that can quickly remove heartburn, acid reflux and hunger pains during another exacerbation. B-2, antacids are a basic “emergency” remedy that a patient can use “on demand” without assistance from others, i.e.е. Without the doctor’s purpose. And thirdly, the introduction of antacids as part of a comprehensive antiulcer therapy increases the effectiveness of healing and promotes more rapid healing of ulcers and erosions. With a suitable course of peptic ulcer disease (rare and brief exacerbations, the absence of large ulcers) antacids can be prescribed even as monotherapy. For moderately severe peptic ulcers, antacids supplement a course of antisecretory drugs. The use of antacids can also be recommended as a way to prevent seasonal exacerbations of acid-dependent diseases.
Antacids have no side effects.
Every drug has side effects, as well as contraindications that limit the possibility of implementation, and antacids are no exception. When taking absorbable antacids, symptoms of alkalosis may appear – loss of appetite, nausea, vomiting, abdominal pain, headache, increased BP. Non-absorbable antacids – constipation or diarrhea, nausea, impaired phosphorus and calcium metabolism, impaired kidney function. The risk of side effects is particularly high with prolonged, continuous use of antacids. Therefore, in all cases where a person is required to continuously take this group of drugs for more than two weeks, it is imperative to consult a doctor and conduct the healing only under his supervision. In addition, it should be taken into account that antacids reduce absorption of many drugs. So there must be a gap of more than two hours between the intake of antacids and all other drugs.
Antacids inhibit digestion.
When used as intended and in the recommended therapeutic doses, no modern antacid product has a negative impact on the digestion of food in the stomach and intestinal tract. Even when taken continuously, antacids are not able to completely neutralize the entire volume of hydrochloric acid formed in the stomach.
During the introduction of antacids, gastric acidity decreases to a pH of 3.0-4.0, at which time digestion, enzyme formation, and food decontamination proceed normally. Moreover, the use of antacids in patients with acid-dependent diseases allows to make better digestion, also digestive motility and absorption of nutrients, which were previously impaired due to excessive levels of acidity of the contents of the stomach.
Antacids can only be used by adults.
In children, acid-dependent diseases can also be. That is why antacids are widely used in pediatrics, for example, in gastritis and gastroduodenitis, reflux esophagitis, multifunctional dyspepsia. Non-absorbable combined antacids containing aluminum and magnesium salts are preferred in this case. Such a combined composition allows for more effective treatment and reduces the risk of side effects. Of the pharmaceutical forms for babies more comfortable suspension and gel, which can be used from 6 years of age. If the baby has situational heartburn, the parents can also use one of the antacid drugs without the help of others. But, of course, it is important not to forget that even a one-time occurrence of heartburn in childhood is a good reason to visit the doctor, which should not be put off forever.